Acetaminophen and Ibuprofen
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temporarily relieves minor aches and pains due to: o headache o toothache o backache o menstrual cramps o muscular aches o minor pain of arthritis
Active ingredients
Strength250 mg + 125 mg
Dosage formTABLET
ManufacturerGranules Pharmaceuticals Inc.
Registration number70010-131-26
Uses and indications
• temporarily relieves minor aches and pains due to: o headache o toothache o backache o menstrual cramps o muscular aches o minor pain of arthritis
Contraindications
• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist • if you have ever had an allergic reaction to acetaminophen or any other pain reliever • right before or after heart surgery
Precautions
Acetaminophen liver damage warning:This product contains acetaminophen. Severe liver damage may occur if you take:with other drugs containing acetaminophenmore than 6 caplets in 24 hours, which is the maximum daily amount for this product3 or more alcoholic drinks every day while using this productAcetaminophen allergy alert: may cause severe skin reactions. Symptoms may include: skin reddeningblistersrashIf skin reaction occurs, stop use and seek medical help right away.NSAID allergy alert: ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:hivesfacial swellingasthma (wheezing)shockskin reddeningrashblistersIf an allergic reaction occurs, stop use and seek medical help right away.NSAID stomach bleeding warning:This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:are age 60 or olderhave had stomach ulcers or bleeding problemstake a blood thinning (anticoagulant) or steroid drugtake other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others]have 3 or more alcoholic drinks every day while using this producttake more or for a longer time than directedHeart attack and stroke warning:NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.
Dosage
do not take more than directedadults and children 12 years and overtake 2 caplets every 8 hours while symptoms persist children under 12 yearsask a doctordo not take more than 6 caplets in 24 hours, unless directed by a doctor
References
Source: DailyMed, U.S. National Library of Medicine. Label published Oct 12, 2026. Set ID: 0f8b9524-8fe3-47cf-bacd-93047442d90d.
Important: The information on this page is provided for reference only and is not a substitute for diagnosis, prescribing, or treatment guidance from a doctor or pharmacist.